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Moderate alcohol intake may diminish amyloid-β synthesis, but substantial alcohol use is associated with Alzheimer’s disease due to the aldehyde mechanism within the amyloid cascade theory, exacerbated by APP overproduction in transgenic mice [115]

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Cortisol and hypothalamic–pituitary–gonadal axis hormones in follicular-phase women with fibromyalgia and chronic fatigue syndrome and effect of depressive symptoms on these hormones