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These findings indicate that repeated intravesical PRP alleviates IC/BPS-related pain and urinary symptoms primarily by reversing T-cell exhaustion and enhancing mitochondrial metabolic status, thus highlighting T-cell immunometabolic modulation as a key therapeutic mechanism

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As mentioned earlier, a lack of adenosylcobalamin leads to the accumulation of toxic methylmalonic acid (MMA), which forces the body to build weak, abnormal fatty acids into the nerve sheaths