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For example, one study showed that in people with type 2 diabetes, treatment with semaglutide (1 mg weekly) causes an average loss of about 6% of body weight over 40 weeks, while treatment with tirzepatide (15 mg/week) leads to an 11% weight loss in this population

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In primary care, orlistat is commonly prescribed, working by inhibiting pancreatic lipase to reduce dietary fat absorption