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The deficiency or mutation of the enzyme has been linked with various disease conditions and abnormalities.39 ZΓ‘mockΓ½ and Koller associated oxidative DNA damage and subsequent risk of cancer susceptibility in individuals with genetic polymorphisms and altered gene expressionβ/activity in catalase.40 Development of mental disorder has also resulted from polymorphism in the catalase-encoding gene.41 In addition, humans with low catalase levels (acatalasemia) are said to be more predisposed to type 2 diabetes mellitus (Fig
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Frequency decreases to 5x per week during remodeling in weeks 5β8 and 2-3x per week during maintenance in weeks 9β12
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