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Interestingly, complex ACNs from fruit extracts or powders were more effective in reducing HbA1c than purified ACN supplements

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Concurrently, it downregulated the mRNA expression of ileal fibroblast growth factor 15 (FGF15) and β ‐Klotho, thereby promoting de novo bile acid synthesis and enhancing cholesterol catabolism and excretion, which collectively contribute to its anti‐atherosclerotic efficacy (Wang, Guan, et al