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Vitamin C facilitates dopamine neuron differentiation in fetal midbrain through TET1- and JMJD3-dependent epigenetic control manner

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In melanocytes 4-HNE, through adduct formation, alters protein function, contributing to oxidative stress-induced cellular dysfunction, which mainly concerns on the functioning of cellular antioxidant system, acceleration of protein degradation, inhibition of melanocyte proliferation, photoaging processes, but also disruption of the intercellular interactions between melanocytes and keratinocytes 101–103