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These findings in HEK293 cells suggest that in this cell type involvement of PKC activation in morphine-induced desensitization may involve phosphorylation of other proteins in addition to direct phosphorylation of MOR

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Results Diabetes increases CAP incidence (relative risk 1.73, 95% CI 1.46‐2.04), hospitalization (+30%‐50%), and 30-day mortality (odds ratio 1.67, 95 % CI 1.45-1.92)

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