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Currently there is some debate about whether the current B12 recom­mendations are sufficient to achieve optimum vitamin B12 status (Doets et al., 2013)

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Understanding your genetic predisposition in GLP-1 pathways can support a more informed conversation with your provider about whether oral or injectable B12 is appropriate for your individual risk profile and whether more frequent baseline and follow-up testing is warranted before starting semaglutide