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Recessive mutations in genes coding for enzymes of the kynurenine pathway — namely kynureninase and 3-hydroxyanthranilic-acid 3,4-dioxygenase — lead to combined vertebral, anal, cardiac, tracheo-esophageal, renal, and limb (VACTERL) congenital malformations (76)

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DCSs provide comprehensive care addressing medical, behavioral and social aspects of dementia through the development of care plans tailored to the needs and goals of each patient living with dementia and their caregiver