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Although Gpx31-GFP and Gpx32-GFP were produced at lower levels in the cap1Δ/Δ strain after exposure to t-BHP for 60 m, this change could be due to the highly increased ROS sensitivity of cap1Δ/Δ affecting protein production

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OS is the most common mechanism underlying accelerated telomere shortening, leading to a number of pathologies including cancer, cardiovascular diseases, diabetes, obesity, and atherosclerosis [16]